Several medications containing Losartan are being recalled. (Black Press file photo)

Potential ‘human carcinogen’ leads to recall of Losartan-containing drugs

Health Canada is advising that there is no immediate risk to patients taking these medications

Multiple high blood pressure medications containing Losartan are being voluntarily recalled due to a “potentially human carcinogen,” Health Canada says.

Teva Canada, Apotex Inc., Pharmascience Inc,m and Pro Doc Limitée are recalling lots of Losartan-containing drugs because of the potential for a nitrosamine impurity, N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) – a potential human carcinogen meaning that long-term exposure could increase the potential risk of cancer.

As with previous recalls involving nitrosamine impurities, Health Canada is advising that there is no immediate risk to patients taking these medications since the potential risk of cancer is with long-term exposure to the impurities.

“Patients should not stop taking their medication unless advised to do so by their healthcare provider,” Health Canada says.

Teva Canada is voluntarily recalling two lots of combination Losartan/hydrochlorothiazide (HCTZ) tablets after testing of one lot identified levels of NMBA above what is considered reasonably safe if the drug were taken over a lifetime. Apotex Inc., Pharmascience Inc., and Pro Doc Limitée are voluntarily recalling multiple lots of Losartan-containing products as a precaution.

The Losartan active pharmaceutical ingredient (API) in all of the recalled products is manufactured by Hetero Labs Ltd. Unit 1, in India. These recalls represent all lots of drugs distributed in Canada that contain Losartan API manufactured at Hetero Labs Ltd. Unit 1.

Related: Children’s strawberry-flavoured medicines recalled due to faulty safety cap

Related: Brewer’s yeast recall for peanut allergies

Losartan is an angiotensin receptor blocker (ARB) drug, also known as a “sartan.” Sartans are a class of drugs used to treat patients with high blood pressure to help prevent heart attacks and stroke. They are also used in patients who have had heart failure or a recent heart attack. There have been multiple recalls of products containing another sartan, valsartan, in Canada and internationally since July 2018 because of nitrosamine impurities (see links below for more information).

There are alternative products currently available on the Canadian market.

Health Canada continues to monitor the supply situation. Health Canada encourages Canadians to visit drugshortagescanada.ca for information on drug shortages and discontinuances. Patients with questions or concerns about any drug they are taking, including on what to do if that drug is not readily available, should speak to their healthcare professional.

For a list of affected products, visit healthycanadians.gc.ca.


@VernonNews
newstips@vernonmorningstar.com

Like us on Facebook and follow us on Twitter.

Just Posted

Port Alice Scotiabank branch closure bad for business and elderly

Port Alice is going through a transition to a more diversified economy that includes tourism.

VIDEO: North Island Bantam Eagles blast Kelowna Rockets in first game of the Championships in Port Hardy

The Eagles are back in action at 7:30 p.m. tonight against the Dawson Creek KFC Canucks.

Mowi Canada West releases statement on Nanaimo teenager’s workplace death

“Our thoughts are with the family at this time, all of us at Mowi are devastated by this tragedy.”

MLA Claire Trevena talks 12 new licensed child care spaces to Port Hardy

“Parents have struggled to find adequate child care for years”

Defiant vigil starts healing in New Zealand after massacre

Police say the gunman in the shooting that killed 50 acted alone

Avalanche warning issued for all B.C. mountains

Warm weather to increase avalanche risk: Avalanche Canada

Privy Council clerk Michael Wernick retires

Jody Wilson-Raybould has accused Wernick of pressuring her to head off criminal charges for SNC-Lavalin

Temperature records dating back to 1947 broken in B.C.

The Squamish airport recorded the hottest temperature in the province (and Canada) on Sunday: 21.3 C

B.C. First Nations’ intake of essential nutrients could drop by 31%: study

Professors project the nutrient decrease by 2050 if climate change mitigation continues as is

Man enters unlocked B.C. home with knife, sexually assaults 22-year-old

Investigation ongoing after woman sexually assaulted in Greater Victoria early Sunday morning

Trudeau fills vacancy in cabinet with B.C. MP Joyce Murray

Murray, 64, was elected in 2008 and served previously as a minister in B.C.’s provincial government

Gunman kills 3 on Dutch tram; mayor says terror likely

Utrecht police release photo of 37-year-old man born in Turkey who is ‘associated with the incident’

Facebook announces changes to political advertising to meet new federal rules

Bill C-76 bans the use of money from foreign entities to conduct partisan campaigns

Most Read